Introduction
Over the last two decades, breakthroughs in the research methodologies employed by experimental physiologists and clinical scientists have paved the way for an explosion in the quality and quantity of available data. These developments have underpinned many of the post-genomic era's advances in understanding, enabling the analysis of specific physiological systems through the collection of unique individual data sets. In parallel with these experimental developments, advances in computational and numerical techniques have accelerated our capacity to derive new knowledge; making possible the integration of multiple data sets through the application of bio-physically based computational models. These modelling developments now provide the potential for analysing complex cause and effect relationships and facilitating the development of improved mechanistic understanding in a range of physiological systems. Through the efforts of an active and multi-disciplinary research community the heart has emerged as arguably the most advanced current exemplar of this approach.
Building on the momentum generated from the previous Cardiac Physiome Workshops held in Oxford (2006), Auckland (2008), Cambridge (2009) the 4th Cardiac Physiome workshop was held in Oxford July 8th-10th 2011. The workshop was residential and all sessions and participants were accommodated at Merton College in the middle of Oxford, a unique venue for both the formal and informal parts of the program. The focus of the meeting continued our theme of combining both experimental and modelling research focused on understanding function across physiological scales in the heart.
Speakers
Covering this scope, plenary talks were given by:
Don Bers (University of California, Davis), an international research leader in the area of cellular and molecular factors involved in the control of cardiac muscle contraction, particularly as modulated by intracellular calcium.
Nicholas Ayache (INRIA, Asclepios), who leads a research group focused on biomedical image analysis and simulation across a number of cardiovascular applications. He is also the editor in Chief of Medical Image Analysis and has been a scientific consultant for several industrial companies in image processing, computer vision, and biomedical imaging.
Yoram Rudy (Washington University in St Louis), whose research is aimed at understanding the mechanisms of cardiac arrhythmias and how they lead to sudden death. He has pioneered theoretical approaches to study these phenomena at various levels of the cardiac system.
Video clips of other speakers at the event will also be available here soon;
| - Dan Beard (Wisconsin) | - Eliot McVeigh (John Hopkins) |
| - Martin Bishop (Oxford) | - Martyn Nash (Auckland) |
| - Oscar Camara (University Pompeu Fabra) | - Steven Niederer (KCL) |
| - Edmund Crampin (Auckland) | - Perumal Nithiarasu (Swansea) |
| - Herve Delingette (INRIA) | - David Nordsletten (KCL) |
| - Olaf Doessel (Karlsruhe) | - Stig Omholt (Oslo) |
| - Igor Effimov (Washington, St Louis) | - Axel Pries (Berlin) |
| - David Eisner (Manchester) | - Reza Razavi (KCL) |
| - Daniel Ennis (California) | - Espen W. Remme (Oslo) |
| - Alberto Figueroa (Stanford) | - Blanca Rodriguez (Oxford) |
| - Alex Frangi (University Pompeu Fabra) | - Frank Sachse (Utah) |
| - Alan Garfinkel (UCLA) | - Michael Sacks (Pittsburgh) |
| - Boyce Griffith (New York) | - Tim Secomb (Arizona) |
| - Jeff Holmes (Virginia) | - Gunnar Seemann (Karlsruhe) |
| - Rod Hose (Sheffield) | - Maxime Sermesant (INRIA) |
| - Chae Hun Leem (Ulsan College of Medicine) | - Rebecca Shipley (Oxford) |
| - William Klug (UCLA) | - Spencer Sherwin (Imperial) |
| - Peter Kohl (Imperial College London) | - Eun Bo Shim (Kangwon National University) |
| - Rob Krams (Imperial College London) | - Bruce Smaill (Auckland) |
| - Martin Krueger (Karlsruhe) | - Christian Soeller (Auckland) |
| - Pier Lambiase (UCL) | - Jos Spaan (Amsterdam) |
| - Jack Lee (KCL) | - Seiryo Sugiura (Tokyo) |
| - Denis Loiselle (Auckland) | - Natalia Trayanova (John Hopkins) |
| - Xiaoyu Luo (Glasgow) | - Richard Vaughan-Jones (Oxford) |
| - Harald Martens (Norwegian University of Life Sciences) | - Jeroen van den Wijngaard (Amsterdam) |
| - Satoshi Matsuoka (Kyoto) | - Alistair Young (Auckland) |
| - Andrew McCulloch (California) | - Henggui Zhang (Auckland) |
Participants included
| - Laura Bear (Auckland) | - Stefano Morotti (Bologna) | |
| - Benjamin Bhattacharya-Ghosh (UCL) | - Harish Narayanan (Simula) | |
| - Bojan Blazevic (KCL) | - Froukje Nolte (Amsterdam) | |
| - Radomir Chaniniok (KCL) | - Fernando Otaviano Campos (Graz) | |
| - Lara Charawi (Milan) | - Michelangelo Paci (Bologna) | |
| - Rajiv Chaturvedi (Toronto) | - Alexander Panfilov (Utrecht) | |
| - Georges Christe (INSERM) | - Ali Pashaei (UPF) | |
| - Andrew Cookson (KCL) | - Joanna Perkins (Oxford) | |
| - Andrew Crozier (KCL) | - Andrew Pullan (Auckland) | |
| - Adelaide De Vecchi (KCL) | - T Alexander Quinn (Oxford) | |
| - Thomas Eriksson (Graz) | - Vijay Rajagopal (Auckland) | |
| - Thomas Fritz (Karlsruhe) | - Blanca Rodriguez (Oxford) | |
| - Stephen Gilbert (Leeds) | - Cristina Rolandi (Amsterdam) | |
| - Alain Goriely (Oxford) | - Ishani Roy (KCL) | |
| - Myrianthi Hadjicharalambous (KCL) | - Javier Saiz (Valencia) | |
| - Arun Holden (Leeds) | - Alessandro Satriano (Calgary) | |
| - Rodney Hose (Sheffield) | - Tobias Schaeffter (KCL) | |
| - Eoin Hyde (Oxford) | - Janina Schwartz (AMC Amsterdam) | |
| - Xiao Jie (UCL Heart Hospital) | - Stefano Severi (Bologna) | |
| - Peter Kekenes-Huskey (California) | - Maria Siebes (Amsterdam) | |
| - Philip Kilner (Royal Brompton Hospital) | - Radostin Simitev (Glasgow) | |
| - Nathan Kirk (Leeds) | - Ayako Takeuchi (Kyoto) | |
| - Jussi Koivumaki (Eastern Finland) | - Beatriz Trenor (Valencia) | |
| - Pablo Lamata (Oxford) | - Pepijn van Horssen (Amsterdam) | |
| - Pier Lambiase (UCL) | - Monique Van Lier (AMC Amsterdam) | |
| - Sander Land (Oxford) | - Mikael Wallman (Oxford) | |
| - Patricia Lawford (Sheffield) | - Vicky Wang (Auckland) | |
| - Glenn Lines (Simula) | - Mathias Wilhelms (Karlsruhe) | |
| - Chu-Pin Lo (Providence) | - Robert Xi (Oxford) | |
| - Xingshuang Ma (Glasgow) | - Henggui Zhang (Manchester) | |
| - Molly Maleckar (Simula) | - Jichao Zhao (Auckland) |
Programme
Details of the full programme for the event can be found here.
Cardiac Physiome Conference 2012
The 2012 Cardiac Physiome Workshop will be held at the Catamaran Resort Hotel (http://www.catamaranresort.com/) in San Diego, California from October 30th to November 2nd, 2012, right before the Scientific Sessions of the American Heart Association in Los Angeles. The meeting is being sponsored in part by the National Biomedical Computation Resource, and registration and program information will be posted shortly at the NBCR web site (www.nbcr.net). For further information contact Teri Simas
Contact
| Conference Organisers: | |
| - Richard Clayton (Sheffield) | |
| - Peter Hunter (Auckland) | |
| - Andrew McCulloch (UCSD) | |
| - David Paterson (Oxford) | |
| - Nic Smith (KCL) | |
| - Sarah Waters (Oxford) |
